acyclovir is discontinued. It is likely that most cases of acyclovir nephrotoxicity, which is likely due in part to direct tubular toxicity
acyclovir and gentamicin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. ioversol. acyclovir and ioversol both increase nephrotoxicity and/or ototoxicity. Modify Therapy/Monitor Closely. mycophenolate. acyclovir will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance.
Enter a drug name to check for any interactions. amikacin. No Results acyclovir. acyclovir and amikacin both increase nephrotoxicity and/or
acyclovir and gentamicin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. ioversol. acyclovir and ioversol both increase nephrotoxicity and/or ototoxicity. Modify Therapy/Monitor Closely. mycophenolate. acyclovir will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance.
Cyclosporine: (Moderate) Additive nephrotoxicity can occur if cyclosporine is administered with other nephrotoxic drugs such as acyclovir. Monitor renal
The risk or severity of nephrotoxicity can be increased when Acyclovir is combined with Meloxicam. Memantine, Acyclovir may decrease the excretion rate of
vorable outcomes to determine the dose of acyclovir based on body weight.27 Most of the case reports were obese patients who developed acyclovir-induced nephrotoxicity and/or neurotoxicity when they received an acyclovir dose based on their ABW.12,28,30,33,35 Also, a report of high dose of acyclovir 15mg/kg resulted in nephrotoxicity in 2
For decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir induces direct insult to renal tubular cells. We postulated that acyclovir is metabolized by the alcohol dehydrogenas
Enter a drug name to check for any interactions. amikacin. No Results acyclovir. acyclovir and amikacin both increase nephrotoxicity and/or
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