Losartan pharmacokinetics

PHARMACOKINETICS: Losartan increases uric acid excretion. Pharmacokinetics: bioavailability is % mean peak concentrations of losartan and is active

The pharmacokinetics of losartan and its active metabolite are linear with oral losartan doses up to 200 ). CONTRAINDICATIONS. Losartan Potassium Tablets USP

Losartan. In subject area: Nursing and Health Professions. Losartan is a The pharmacokinetic interaction of fluconazole 200 mg/day with losartan 100

half-life. ln-transformed values. Table 1B. Pharmacokinetic Based on the pharmacokinetic parameters of losartan, losartan carboxy.

Pharmacokinetics Absorption : Bioavailability is 33 Drug interaction Losartan NSAIDS Decreases of effect of Losartan

Drug Interactions Losartan, administered for 12 days, did not affect the pharmacokinetics or pharmacodynamics of a single dose of warfarin. Losartan did not affect the pharmacokinetics of oral or intravenous digoxin. There is no pharmacokinetic interaction between losartan and hydrochlorothiazide. Coadministration of losartan and

Drug Interactions Losartan, administered for 12 days, did not affect the pharmacokinetics or pharmacodynamics of a single dose of warfarin. Losartan did not affect the pharmacokinetics of oral or intravenous digoxin. There is no pharmacokinetic interaction between losartan and hydrochlorothiazide. Coadministration of losartan and

pharmacokinetic interaction between losartan and hydrochlorothiazide. Coadministration of losartan and cimetidine led to an increase of about 18% in AUC of losartan but did not affect the pharmacokinetics of its active metabolite. Coadministration of losartan and phenobarbital led to a reduction of about 20% in the AUC of

Based on the pharmacokinetic parameters of losartan, losartan carboxy Good Manufacturing Practice. ICH. International Conference of