Hyperekplexia in adults

Hyperekplexia is a rare neurological disorder that is characterized by an excessive startle response to unexpected stimuli.

Adults: A Narrative Review Revolutionizing Neurological Disorder Treatment Hyperekplexia (348); Meningitis (2197); Meningitis, Aseptic (158)

Rarely, infants with hereditary hyperekplexia experience recurrent seizures (epilepsy). n nHereditary hyperekplexia may explain some cases of sudden infant death syndrome (SIDS), which is a major cause of unexplained death in babies younger than 1 year. n nThe signs and symptoms of hereditary hyperekplexia typically fade by age 1.

Hyperekplexia is characterized by exaggerated startle reflexes and hypertonia in response to sudden unexpected stimuli, typically manifesting in utero or shortly after birth, but also occurring in children or adults. It is a predominantly hereditary paroxysmal neurologic disorder.

Fluoxetine (selective serotonin reuptake inhibitor) was shown to be effective in an adult-onset sporadic hyperekplexia at 20 40 mg/d dosages, especially on the associated anxiety, stress, and the affective state of the patient [47].

the genetic disorder (hyperekplexia, sic.) and the sporadic form (hyperekplexia). 2 Gastaut and Ville-neuve21 corrected the spelling and suggested that the term hyperekplexia be used. Authors aware of this distinction have generally accepted this spelling, though startle disease is still preferable for the sake of clarity.

In both infants and adults, hyperekplexia is treated most effectively with the anti-anxiety and anti-spastic drug clonazepam. Other drugs that may be used

Hyperekplexia is a hereditary condition that affects how a person reacts to unexpected stimuli, such as loud noises. It can also affect adults. Learn more here.

Startle syndromes are heterogeneous groups of disorders with abnormal and exaggerated responses to startling events, including hyperekplexia, stimulus-induced disorders, and neuropsychiatric startle syndromes. Hyperekplexia can be attributed to a genetic, idiopathic, or symptomatic cause.