Paclitaxel versus docetaxel

☑️@paclitaxel_versus_do · 3055 subscribers · Content 18+ 🔞
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Actual: Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) has demonstrated clinical benefit in metastatic breast cancer (MBC) in a randomized phase III trial versus paclitaxel (CA012; N = 454) and in a randomized phase II trial versus docetaxel (CA024; N = 300). This retrospective analysis examines whe
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The taxoids, paclitaxel (Taxol) and docetaxel (Taxotere), represent a novel class of antineoplastic drugs. Paclitaxel and docetaxel share a similar mechanism of action: the promotion of microtubule assembly and inhibition of microtubule disassembly. The clinical development of paclitaxel was initial

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0001). The rate of peripheral sensory neuropathy was increased in the nab-paclitaxel arm at 55.5% grade 3/4 events versus 20.1% with docetaxel (

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In stages I-III only: Cisplatin Carboplatin Paclitaxel (Taxol) Albumin-bound paclitaxel (nab-paclitaxel, Abraxane) Docetaxel (Taxotere).

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Lung cancer cisplatin carboplatin paclitaxel albumin-bound paclitaxel docetaxel gemcitabine vinorelbine etoposide

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Versus Treatment of Physician's Choice (TPC) Docetaxel Lipid Suspension (75 mg/m2), Taxotere Registered (100 mg/m2), B013Nab-Paclitaxel

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Median TTP was 21.1 weeks versus 12.7 weeks and median OS 55.7 weeks versus 32 weeks. Toxicity profiles were acceptable with more anemia and neurotoxicity for paclitaxel and more edema and fatigue for docetaxel. In patients with MBC unfit for 3-weekly docetaxel or paclitaxel, weekly administration of either compound may certainly be considered.

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Common chemotherapy drug combinations ; Paclitaxel and carboplatin. Paclitaxel and carboplatin ; Docetaxel and carboplatin. Docetaxel and carboplatin.

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Nab-paclitaxel vs sb-paclitaxel or nab-paclitaxel vs docetaxel. Since there were two types of control arm (sb-paclitaxel arm 2,3 or docetaxel arm 4,5,10), we did further subgroup analysis to see

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Cabazitaxel. Docetaxel. Nab-paclitaxel. Paclitaxel. Vinblastine. Vincristine. Vincristine liposomal. Vinorelbine.

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