Meth and gabapentin

☑️@meth_and_gabapentin · 6155 subscribers · Content 18+ 🔞
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Research highlights. The level of 2 / -1 subunit increased in the limbic forebrain and frontal cortex showing METH-induced sensitization. The development of behavioral sensitization induced by METH was suppressed by co-administration of gabapentin. Gabapentin inhibited METH-induced place preference. Gabapentin may reduce trafficking of 2 / -1 subunit proteins to plasma membrane.

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Research highlights. The level of 2 / -1 subunit increased in the limbic forebrain and frontal cortex showing METH-induced sensitization. The development of behavioral sensitization induced by METH was suppressed by co-administration of gabapentin. Gabapentin inhibited METH-induced place preference. Gabapentin may reduce trafficking of 2 / -1 subunit proteins to plasma membrane.

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Riluzole and gabapentin had no effect on the induction of sensitization to cocaine and METH; however, they attenuated the expression of sensitization to METH but not to cocaine. These findings suggest that riluzole- and gabapentin-mediated changes in EAA and GABAergic transmission, respectively, had

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