Anaerobes: Similar anaerobic coverage as compared to penicillin-G. (5) Gram negative coverage: Doxycycline has reasonably good coverage for E.
While the 2024 CDC guideline for PID does not definitively support anaerobic coverage, the addition of metronidazole to the outpatient ceftriaxone/doxycycline
Anaerobic coverage (e.g, metronidazole plus cefepime produces coverage for atypical pathogens (with azithromycin or doxycycline).
anaerobic coverage.[19] The exception to this would be intra Bactrim, doxycycline, and clindamycin can be used orally to treat less
While the 2024 CDC guideline for PID does not definitively support anaerobic coverage, the addition of metronidazole to the outpatient ceftriaxone/doxycycline
coli, and Enterobacter species, and some anaerobic coverage including Clostridial species. Doxycycline is most commonly an oral prescription and there is
Cephalosporins and fluoroquinolones have minimal anaerobic coverage. If MRSA coverage needed or PCN allergic: Doxycycline/TMP-SMX/clindamycin.
The king of anaerobic coverage, Flagyl is often added to regimens that have insufficient anaerobic coverage. Bactrim. Doxycycline. PO. Bactrim.
Finally, fourth-generation agents improve gram-positive coverage, maintain gram-negative coverage, and gain anaerobic coverage. 10. doxycycline (Vibramycin), and fluoroquinolones.
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