Max dose of methadone
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Max dose is 300 mg bid. Reduce dose in renal Total daily oral morphine dose. Estimated oral methadone as a % of total daily morphine.
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IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Current Infusion Dose Recommended Scheduled Dosing PRN Dosing Midazolam Drip IV Lorazepam (Max Dose: 4 mg) PRN IV Lorazepam (Max Dose: 4 mg)
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Max dose is 300 mg bid. Reduce dose in renal Total daily oral morphine dose. Estimated oral methadone as a % of total daily morphine.
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IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 IV Lorazepam (Max Dose: 4 mg). PRN IV Lorazepam (Max Dose: 4 mg). 0.06 mg
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IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Current Infusion Dose Recommended Scheduled Dosing PRN Dosing Midazolam Drip IV Lorazepam (Max Dose: 4 mg) PRN IV Lorazepam (Max Dose: 4 mg)
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Max 3 doses in 24hrs. On day 4/5 – doses consolidated. Hold 10mg PRN dose Methadone 40mg PO OD starting dose. Addition of Hydromorphone IR
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The methadone max dose for pain is 100mg daily. The use of this medication higher than this dose would result in an overdose which has its signs
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Grapefruit juice. Carbamazepine. Phenytonin. Rifampicin/rifampin. St Methadone 10mg q3h PRN. Max 3 doses in 24hrs. On day 4/5 – doses
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Note: seek advice from the PCU clinical staff before any increase in the dose of methadone or ketamine. Max dose is 300 mg bid. Reduce dose
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