Both drugs are classified as benzodiazepines. They work by increasing the activity of GABA, or gamma-aminobutyric acid, in the brain. The neurotransmitter GABA
The activity of most GABA type-A (GABA-A) receptors (those containing These drugs increase the inhibitory action of GABA. Specific physiological
Both drugs are classified as benzodiazepines. They work by increasing the activity of GABA, or gamma-aminobutyric acid, in the brain. The neurotransmitter GABA
GABA (gamma-aminobutyric acid) regulation: GABA is an inhibitory drugs or alcohol, increasing their risk of developing addiction.
Tiagabine is the latest of the new antiepileptic drugs. It inhibits GABA reuptake, thereby increasing GABA levels. The drug is highly protein-
In doing so, the drug increases the receptors' affinity for GABA, an inhibitory neurotransmitter. Enhanced GABA activity reduces the
A GABA agonist is a drug which acts to stimulate or increase the action at the GABA receptor, producing typically sedative effects
GABA and its receptors have been major targets for drug development. Drugs that activate GABA receptors (called agonists) or increase the
Furthermore, drugs targeting GABA A receptors, and NASs bind the GABA A receptor at allosteric sites and increase the GABA A receptor current by increasing chloride conductance . The presence
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