The main treatments for a GIST are surgery and targeted therapy drugs. Chemotherapy is not a helpful treatment for GISTs. Radiotherapy is rarely used. Risk groups. After surgery to remove a GIST, doctors decide whether it is low-risk or high-risk. They look at where the GIST started, its size and mitotic rate.
Imatinib (Gleevec), a targeted therapy drug, is often the first treatment used for patients with GIST. However, patients with advanced GIST or those unable to continue taking the drug, often due to adverse events, need different options. In this case, the current second-line standard of care treatment for this patient population is sunitinib.
Drugs Used to Treat Advanced GIST. Imatinib (Gleevec) Most people with advanced GIST take imatinib at some point in their treatment. Imatinib is usually the first targeted therapy drug doctors use
by calling the PBS Complex Drugs Programs enquiry line. Continuing PBS-subsidised treatment with imatinib to treat resected primary GIST with
treatment of Gastrointestinal Stromal Tumors (GIST), not Muc1. Targeted Therapy - Molecular Targeted Drugs: These include antibody-drug
The three targeted drugs that are used for GIST are Imatinib, Sunitinib, and Regorafenib. Imatinib is the first treatment choice for GIST patients. It is
by JC Baranda 2024drug screen of FDA-approved drugs in GIST cells that four drugs Beyond standard therapy: drugs under investigation for the treatment
TKIs approved to treat GIST currently include imatinib (Gleevec ), sunitinib (Sutent ), and regorafenib (Stivarga ). Although these drugs represent an important advance in GIST treatment, resistance to TKIs eventually develops. But researchers now better understand how this resistance arises in patients with GIST.
GIST-Treatment Localized GIST Surgery is the definitive therapy therapy and the development of new agents for drug resistant GISTs; 36.
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