Long QT syndrome (LQTS) is a disorder of cardiac repolarization drugs to avoid in congenital LQTS. This site is updated regularly with free
Acquired LQTS Drug-induced LQTS: Usually substances that block potassium outflow during the rapid repolarization phase Electrolyte imbalances:
drug-induced LQTS. Antenatal diagnosis. Prenatal diagnosis should be considered when one of the parents has LQTS. Genetic counseling. Inheritance may be
Drug-induced LQTS is an iatrogenic response to drugs that mimics congenital LQTS. Because of the phenotypic overlapping, it was originally thought that a large proportion of drug-induced LQTS could manifest in carriers of incompletely penetrant mutations located on genes linked to congenital LQTS. 3 Today, it is clear that 10% of patients with
An important consideration is that patients who are diagnosed with acquired LQTS may in fact have underlying congenital LQTS that is unmasked with QT-prolonging drugs. 43 In an international cohort of patients with apparent acquired LQTS, about one-fourth of patients harbored a pathogenic LQTS gene variant. 44 Hence, patients with
All patients with LQTS should avoid medications contra-indicated in LQTS. A list of these drugs can be found on the net under 'LQT drugs' Those with a long QT
Congenital LQTS and Drugs to Avoid List. There are over 290 medicines on the Drugs to Avoid (DTA) list for patients with Congenital LQTS (CLQTS).
Acquired LQTS may occur secondary to ingestion of QT interval-prolonging drugs, electrolyte imbalances, or bradyarrhythmias. Patients with LQTS
Drug-induced LQTS is the most common cause of a-LQTS; as a matter of fact, a survey by Schwartz et al [3] of 670 patients in the International LQTS Registry revealed that anesthesia can trigger LQTS.
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