Methotrexate omeprazole

☑️@methotrexate_omepraz · 4093 subscribers · Content 18+ 🔞
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Actual: We report a case of methotrexate toxicity potentially induced by a drug interaction between methotrexate and omeprazole in a 25-year-old man with osteosarcoma. The patient was placed on omeprazole
4.8 rating 2025-04-24
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interactions: co-administration of methotrexate and omeprazole has resulted in delayed renal elimination of methotrexate. In one case in which methotrexate was

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Methotrexate. Omeprazole may increase the effects of methotrexate. Your doctor may adjust your dose depending on the levels of methotrexate in your body. Diazepam.

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Methotrexate, The serum concentration of Methotrexate can be increased when it is combined with Omeprazole. Methsuximide, The metabolism of Methsuximide can

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Both Methotrexate and Olaparib can increase the risk of myelosuppression. Omeprazole. Omeprazole decreases the clearance of Methotrexate (high-dose).

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omeprazole, esomeprazole, and pantoprazole, with methotrexate (primarily at high dose), may elevate and prolong serum levels of methotrexate.

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Omeprazole and Methotrexate. Omeprazole can increase the blood levels and side effects of methotrexate. Concomitant use of the two drugs may elevate and prolong serum concentrations of methotrexate and its metabolite hydroxymethotrexate, possibly leading to methotrexate toxicities. Omeprazole and Clopidogrel (Plavix)

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There is evidence that co-administration of methotrexate and omeprazole prolongs the elimination of methotrexate via kidneys. Co-administration of proton

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The serum concentration of Methotrexate can be increased when it is combined with Omeprazole. Metabolizes methotrexate (MTX) to polyglutamates.

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Omeprazole taken with clopidogrel can lower the activity of clopidogrel, so avoid taking these drugs together. Taking omeprazole with methotrexate may result in high levels of methotrexate or methotrexate toxicity. Your doctor may temporarily stop omeprazole treatment if you are taking a high dose of methotrexate.

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