As anticancer drugs, nucleosides belong to a class of antimetabolites, a category that encompasses purine or pyrimidine analogs (nucleosides), folic acid and amino acid analogs, and ribonucleotide reductase inhibitors. [5]
6. Nucleoside Analogs as Anti-HCoV Drugs. Nucleoside analogs are widely used as drugs against infections caused by herpes viruses, hepatitis B virus, human immunodeficiency virus (HIV) but also against RNA virus infections such as hepatitis C .
MECHANISMS OF DRUG RESISTANCEAcyclovir, famciclovir, and valacyclovir are antiviral agents within the nucleoside analog class. After
Nucleoside/nucleotide reverse transcriptase inhibitors, also called nucleoside analogs, such as abacavir, emtricitabine, and tenofovir. These medicines are
by N Borbone 2024 Cited by 76Nucleoside Analogs as Anti-HCoV Drugs. Nucleoside analogs are widely used as drugs against infections caused by herpes viruses, hepatitis B
analogs into medicines. The company, through its technology, is purine and pyrimidine-based nucleosides as potential drug candidates. The
Nucleoside analogs play a crucial role in the production of high-value antitumor and antimicrobial drugs. Currently, nucleoside analogs are mainly obtained through nucleic acid degradation, chemical synthesis, and biotransformation.
For example, the antiviral drug acyclovir is a nucleoside analog that is used to treat herpes simplex virus infections. Anticancer drugs: Nucleosides can also
Valacyclovir is an antiviral drug that belongs to the purine (guanine) nucleoside analog drug class.¹. As a prodrug to acyclovir (Zovirax)
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