Abuse of gabapentinoids

The gabapentinoids, pregabalin and gabapentin are abused and misused particularly by those with a history of drug abuse. Those with an opioid use disorder seem to be more prone to abuse gabapentinoids than patients with other substance use disorders.

Results: 22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate

Concurrent abuse of gabapentinoids with illicit drugs can exacerbate drug-related damages. Drug screening and postmortem toxicology tests have revealed an increase in gabapentinoid consumption. In response to the abuse potential, several countries have classified gabapentinoids as controlled substances.

Background/aims: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.

Conclusion Evidence suggests gabapentinoids possess potential for abuse, particularly in individuals with a history of opioid abuse, and reports of such abuse

Synonyms were combined. (abuse: misuse, opioids: opioid, drug abuse: drug misuse, addiction: dependence, gabapentinoids: gabapentinoid), after

Reports of gabapentinoid abuse alone, and with opioids, have Gabapentinoid products include gabapentin, which is marketed under the name

Gabapentin (/- pregabalin) has the best evidence for efficacy. Increased concern regarding abuse or misuse of gabapentinoids. Gabapentinoid use in ESRD

Synonyms were combined. (abuse: misuse, opioids: opioid, drug abuse: drug misuse, addiction: dependence, gabapentinoids: gabapentinoid), after