Understanding the interactions of amlodipine with other medications is integral to ensuring its safe use. Amlodipine’s interactions primarily involve drugs that impact its metabolism or those that might enhance its effects. a. Metabolic Interactions. Amlodipine is metabolized in the liver, primarily through the cytochrome P450 3A4 enzyme.
The metabolism of Amlodipine can be increased when combined with Methylprednisolone. Methylprednisone, The metabolism of Methylprednisone can be decreased
responsible for metabolism of amlodipine; therefore, administration of amlodipine with been reported after oral administration of amlodipine.
Amlodipine besylate and amlodipine aspartate significantly decreased liver injury and hepatic steatosis, and improved lipid metabolism with
follow the same route of responsible for metabolism of amlodipine; therefore, administration of amlodipine with grapefruit.
After the administration of therapeutic doses of amlodipine to patients diagnosed with hypertension, amlodipine Sildenafil, The metabolism of Sildenafil can
Understanding the interactions of amlodipine with other medications is integral to ensuring its safe use. Amlodipine’s interactions primarily involve drugs that impact its metabolism or those that might enhance its effects. a. Metabolic Interactions. Amlodipine is metabolized in the liver, primarily through the cytochrome P450 3A4 enzyme.
Interaction : Itraconazole and Fluconazole: Inhibits amlodipine metabolism. Rifampicin: Decreases effects of amlodipine. Cyclosporine: Levels of
amlodipine to patients diagnosed with hypertension, amlodipine causes The metabolism of Ibuprofen can be decreased when combined with Amlodipine.
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