Cyp450 drugs list

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Actual: Many drugs are metabolized by more than one CYP450 enzyme, and this is especially true for CYP2C19, where it is often a secondary pathway. Nonetheless, in some drugs, CYP2C19 is known to be the primary pathway, and these are listed with an asterisk () in Table 1. Many of the other drugs in Table 1 are metabolized primarily by other CYP450 enzymes.
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Interactions with Drugs Affecting CYP450 Isoenzymes: The effects of concomitant use or discontinuation of CYP450 3A4 inducers/inhibitors or CYP450 2D6 inhibitors are complex; concomitant use requires careful consideration of the effects on the parent drug, codeine, and the active metabolite, morphine.

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Lorazepam is metabolized differently from these common benzodiazepines, SSRIs, and SNRIs. Metabolic Pathway. Medication, CYP450 2C19, CYP450 2D6, CYP450 3A4

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Concomitant use or discontinuation of CYP450 isoenzymes including CYP450 3A4 inducers, CYP450 3A4 inhibitors, or CYP450 2D6 inhibitors are complex; concomitant use requires careful consideration of the effects on the parent drug, tramadol, and the active metabolite, M1.

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by M Deodhar 2024 Cited by 49The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions.

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Drugs that induce CYP450 enzymes taking metronidazole with phenytoin, phenobarbital, or other drug that stimulate CYP450 enzymes can cause metronidazole to leave the body too quickly; Please note that this list may not be complete, and other interactions with drugs not listed here may occur. Metronidazole and Clindamycin

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Compounding this is the laundry list of enzyme inhibitors for CYP450 2D6, involved in changing the metabolism of aripiprazole if taken

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Drugs interfering with the cytochrome P450 (CYP450) enzyme system should be avoided with bedaquiline. This list is not exhaustive.

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For example, co-administered drugs that are also metabolized by. CYP450 enzymes used by the opioids or that inhibit CYP450 2D6 cause decreased metabolism, see

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Drugs that induce CYP450 enzymes taking metronidazole with phenytoin, phenobarbital, or other drug that stimulate CYP450 enzymes can cause metronidazole to leave the body too quickly; Please note that this list may not be complete, and other interactions with drugs not listed here may occur. Metronidazole and Clindamycin

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