Levothyroxine and ppi timing

There are possible interactions of PPIs with other frequently prescribed drugs, such as levothyroxine, digoxin, benzodiazepines and

Keywords: Levothyroxine and PPIs, drug interaction, Levothyroxine, PPIs, Protonix, Pantoprazole, Heartburn, GERD, thyroid, pregnancy category

Drug-drug interactions between levothyroxine and St. John's Wort and between levothyroxine and proton- pump inhibitors (PPIs) may alter

Levothyroxine falls into this group and is the most commonly Proton pump inhibitors (PPIs), such as omeprazole or pantoprazole

Proton pump inhibitors (PPIs): PPIs, such as Prilosec Factors influencing the levothyroxine dose in the hormone replacement therapy of primary

absorbing levothyroxine therapy. A recent study has shown that taking a PPI can have a significant effect on the absorption of levothyroxine tablets.

Tapering to stop any unnecessary PPI use, and rescheduling doses of the PPI, oral iron and levothyroxine, can help reduce the adverse interactions of these

One study found that replacing levothyroxine tablets with an oral solution improved levothyroxine absorption in the presence of PPIs. 8.

Consider the alteration in gastric pH caused by the PPI. Some authorities recommend separating administration of PPI and levothyroxine by several hours, however