Half life of celecoxib

Sulindac (half-life approx. hours): 4 days (based on active metabolite) Tenoxicam (half-life 72 hours): 15 days COX-2 selective inhibitors (e.g. celecoxib

Half life, 7.8 hours; 11 hours (mild hepatic impairment); 13 hours Celecoxib (celecoxib) is chemically designated as 4-[5-(4

The effective terminal half-life is about 11 hours. Celecoxib is distributed into breast milk. The pharmacokinetics of celecoxib may vary in different

Other celecoxib brands include: Elyxyb Cambia, Cataflam, Lofena, Voltaren, Zipsor, Zorvolex Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

prolongs the absorption process making terminal half-life (t1/2) CELEBREX celecoxib capsules. 819 058 004. P . CELEBREX celecoxib capsules.

Celecoxib and etoricoxib are well absorbed from the gut. They are eliminated by hepatic metabolism. The half-life of celecoxib is 11 hours, while that of etoricoxib is longer (25 hours). Parecoxib can be given by intramuscular or intravenous injection for control of postoperative pain and has a half-life of 5 9 hours.

PRODUCT: Celebrex (celecoxib) Capsules, 100 mg 200 mg. SPONSOR: Searle. 4901 half-life appear longer than the true elimination half-life of the drug.

2.3.Classification of NSAIDs on the basis of plasma half-life (t ). NSAIDs can also be divided into short-acting (plasma half-life less than 6 h) such as aspirin, diclofenac and ibuprofen and long-acting (half-life approximately greater than 10 h) such as naproxen, celecoxib.

Celecoxib has a half-life of about 11 hours. A drug's half-life is the length of time it takes for half a dose of the drug to be removed